A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression

CD45 (leukocyte common) antigen is a hemopoietic cell-specific tyrosine phosphatase essential for antigen receptor-mediated signaling in lymphocytes. The molecule undergoes complex alternative splicing in the extracellular domain, and different patterns of CD45 splicing are associated with distinct...

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Detalhes bibliográficos
Main Authors: Stanton, Tara, Boxall, Sally, Hirai, Kouzo, Dawes, Ritu, Tonks, Susan, Yasui, Tomoyo, Kanaoka, Yasushi, Yuldasheva, Nadira, Ishiko, Osamu, Bodmer, Walter, Beverley, Peter C. L., Tchilian, Elma Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156315/
https://ncbi.nlm.nih.gov/pubmed/12716971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0931490100
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