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A nonsense mutation in the first transmembrane domain of connexin 43 underlies autosomal recessive oculodentodigital syndrome

BACKGROUND: Oculodentodigital syndrome (ODD) is a pleiotropic congenital disorder characterised by abnormalities of the face, eyes, dentition, and limbs. ODD, which is inherited as an autosomal dominant trait, results from missense mutations in the gap junction protein connexin 43. OBJECTIVE: To ana...

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Bibliografiset tiedot
Päätekijät: Richardson, R J, Joss, S, Tomkin, S, Ahmed, M, Sheridan, E, Dixon, M J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Group 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564566/
https://ncbi.nlm.nih.gov/pubmed/16816024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.037655
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