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A nonsense mutation in the first transmembrane domain of connexin 43 underlies autosomal recessive oculodentodigital syndrome

BACKGROUND: Oculodentodigital syndrome (ODD) is a pleiotropic congenital disorder characterised by abnormalities of the face, eyes, dentition, and limbs. ODD, which is inherited as an autosomal dominant trait, results from missense mutations in the gap junction protein connexin 43. OBJECTIVE: To ana...

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Detalhes bibliográficos
Main Authors: Richardson, R J, Joss, S, Tomkin, S, Ahmed, M, Sheridan, E, Dixon, M J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564566/
https://ncbi.nlm.nih.gov/pubmed/16816024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.037655
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