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Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

Induction of an altered phenotype by prenatal under-nutrition involves changes in the epigenetic regulation of specific genes. We investigated the effect of feeding pregnant rats a protein-restricted (PR) diet with different amounts of folic acid on the methylation of individual CpG dinucleotides in...

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Bibliographische Detailangaben
Hauptverfasser: Lillycrop, Karen A, Phillips, Emma S, Torrens, Christopher, Hanson, Mark A, Jackson, Alan A, Burdge, Graham C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564112/
https://ncbi.nlm.nih.gov/pubmed/18186951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0007114507894438
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