Cannabinoid (CB2) receptor deficiency reduces the susceptibility of macrophages to oxidized LDL/oxysterol-induced apoptosis

Macrophage apoptosis is an important process in the pathophysiology of atherosclerosis. Oxidized low-density lipoproteins (OxLDL) are a major component of lesions and potently induce macrophage apoptosis. Cannabinoid receptor 2 (CB2), the predominant macrophage cannabinoid receptor, modulates severa...

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Autors principals: Freeman-Anderson, Natalie E., Pickle, Theresa G., Netherland, Courtney D., Bales, Alicia, Buckley, Nancy E., Thewke, Douglas P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563213/
https://ncbi.nlm.nih.gov/pubmed/18614816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800105-JLR200
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