A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer

BACKGROUND: Germline mutations in the Chek2 kinase gene (CHEK2) have been associated with a range of cancer types. Recently, a large deletion of exons 9 and 10 of CHEK2 was identified in several unrelated patients with breast cancer of Czech or Slovak origin. The geographical and ethnic extent of th...

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Detalles Bibliográficos
Main Authors: Cybulski, C, Wokołorczyk, D, Huzarski, T, Byrski, T, Gronwald, J, Górski, B, Dębniak, T, Masojć, B, Jakubowska, A, Gliniewicz, B, Sikorski, A, Stawicka, M, Godlewski, D, Kwias, Z, Antczak, A, Krajka, K, Lauer, W, Sosnowski, M, Sikorska‐Radek, P, Bar, K, Klijer, R, Zdrojowy, R, Małkiewicz, B, Borkowski, A, Borkowski, T, Szwiec, M, Narod, S A, Lubiński, J
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2006
Assuntos:
Short Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563179/
https://ncbi.nlm.nih.gov/pubmed/17085682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.044974
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