CHEK2 Is a Multiorgan Cancer Susceptibility Gene

A single founder allele of the CHEK2 gene has been associated with predisposition to breast and prostate cancer in North America and Europe. The CHEK2 protein participates in the DNA damage response in many cell types and is therefore a good candidate for a multisite cancer susceptibility gene. Thre...

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Main Authors: Cybulski, C., Górski, B., Huzarski, T., Masojć, B., Mierzejewski, M., Dębniak, T., Teodorczyk, U., Byrski, T., Gronwald, J., Matyjasik, J., Złowocka, E., Lenner, M., Grabowska, E., Nej, K., Castaneda, J., Mędrek, K., Szymańska, A., Szymańska, J., Kurzawski, G., Suchy, J., Oszurek, O., Witek, A., Narod, S. A., Lubiński, J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182149/
https://ncbi.nlm.nih.gov/pubmed/15492928
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