Cancer risks in first-degree relatives of CHEK2 mutation carriers: effects of mutation type and cancer site in proband

It is important to have accurate knowledge of the range of cancers associated with various CHEK2 mutations, and of the lifetime risks of cancer associated with each. We wished to establish the relationship between family history, mutation type and cancer risk in families with a CHEK2 mutation. We ob...

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Detalhes bibliográficos
Main Authors: Gronwald, J, Cybulski, C, Piesiak, W, Suchy, J, Huzarski, T, Byrski, T, Gorski, B, Debniak, T, Szwiec, M, Wokolowczyk, D, Matuszewski, M, Sun, P, Lubinski, J, Narod, S A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694428/
https://ncbi.nlm.nih.gov/pubmed/19401704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605038
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