Cancer risks in first degree relatives of BRCA1 mutation carriers: effects of mutation and proband disease status

BACKGROUND: Mutations in the BRCA1 (MIM 113705) gene are found in many families with multiple cases of breast and ovarian cancer, and women with a BRCA1 mutation are at significantly higher risk of developing breast and ovarian cancer than are the general public. METHODS: We obtained blood samples a...

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Detalhes bibliográficos
Main Authors: Gronwald, J, Huzarski, T, Byrski, B, Medrek, K, Menkiszak, J, Monteiro, A N, Sun, P, Lubinski, J, Narod, S A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564518/
https://ncbi.nlm.nih.gov/pubmed/16227521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.036921
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