Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

The aryl hydrocarbon receptor (AHR) is known for its role in the adaptive and toxic responses to a large number of environmental contaminants, as well as its role in hepatovascular development. The classical AHR pathway involves ligand binding, nuclear translocation, heterodimerization with the AHR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bunger, Maureen K., Glover, Edward, Moran, Susan M., Walisser, Jacqueline A., Lahvis, Garet P., Hsu, Erin L., Bradfield, Christopher A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2008
Gaiak:
Carcinogenicity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563146/
https://ncbi.nlm.nih.gov/pubmed/18660548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn149
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