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Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

The aryl hydrocarbon receptor (AHR) is known for its role in the adaptive and toxic responses to a large number of environmental contaminants, as well as its role in hepatovascular development. The classical AHR pathway involves ligand binding, nuclear translocation, heterodimerization with the AHR...

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Autors principals: Bunger, Maureen K., Glover, Edward, Moran, Susan M., Walisser, Jacqueline A., Lahvis, Garet P., Hsu, Erin L., Bradfield, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563146/
https://ncbi.nlm.nih.gov/pubmed/18660548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn149
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