Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

The identification of nearly a dozen ion channel genes involved in the genesis of human atrial and ventricular arrhythmias has been critical for the diagnosis and treatment of fatal cardiovascular diseases. In contrast, very little is known about the genetic and molecular mechanisms underlying human...

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Hauptverfasser: Le Scouarnec, Solena, Bhasin, Naina, Vieyres, Claude, Hund, Thomas J., Cunha, Shane R., Koval, Olha, Marionneau, Celine, Chen, Biyi, Wu, Yuejin, Demolombe, Sophie, Song, Long-Sheng, Le Marec, Hervé, Probst, Vincent, Schott, Jean-Jacques, Anderson, Mark E., Mohler, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563133/
https://ncbi.nlm.nih.gov/pubmed/18832177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805500105
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