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Structure and DNA binding of alkylation response protein AidB

Exposure of Escherichia coli to alkylating agents activates expression of AidB in addition to DNA repair proteins Ada, AlkA, and AlkB. AidB was recently shown to possess a flavin adenine dinucleotide (FAD) cofactor and to bind to dsDNA, implicating it as a flavin-dependent DNA repair enzyme. However...

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Détails bibliographiques
Auteurs principaux: Bowles, Timothy, Metz, Audrey H., O'Quin, Jami, Wawrzak, Zdzislaw, Eichman, Brandt F.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563087/
https://ncbi.nlm.nih.gov/pubmed/18829440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806521105
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