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Irreversible chemical steps control intersubunit dynamics during translation
The ribosome, a two-subunit macromolecular machine, deciphers the genetic code and catalyzes peptide bond formation. Dynamic rotational movement between ribosomal subunits is likely required for efficient and accurate protein synthesis, but direct observation of intersubunit dynamics has been obscur...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2563075/ https://ncbi.nlm.nih.gov/pubmed/18824686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805299105 |
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