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Irreversible chemical steps control intersubunit dynamics during translation

The ribosome, a two-subunit macromolecular machine, deciphers the genetic code and catalyzes peptide bond formation. Dynamic rotational movement between ribosomal subunits is likely required for efficient and accurate protein synthesis, but direct observation of intersubunit dynamics has been obscur...

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Detalhes bibliográficos
Main Authors: Marshall, R. Andrew, Dorywalska, Magdalena, Puglisi, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563075/
https://ncbi.nlm.nih.gov/pubmed/18824686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805299105
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