HSV-tk/GCV gene therapy mediated by EBV-LMP1 for EBV-associated cancer

BACKGROUND: To investigate the feasibility of gene therapy in treating Epstein-Barr virus (EBV)-associated cancer by employing the suicide gene, herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV), which uses the signaling pathway through the HIV-long terminal repeat (LTR) gene which is e...

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Bibliografiske detaljer
Main Authors: Lifang, Yang, Min, Tang, Midan, Ai, Ya, Cao
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562992/
https://ncbi.nlm.nih.gov/pubmed/18811956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-42
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