Constitutive Activation of AKT Pathway Inhibits TNF-induced Apoptosis in Mitochondrial DNA-Deficient human myelogenous leukemia ML-1a

TNF plus protein synthesis inhibitor cycloheximide induced apoptosis in human myelogenous leukemia ML-1a but not in C19, respiration minus mitochondrial DNA deficient C19 cells, derived from ML-1a. To investigate how mitochondrial DNA depletion inhibits apoptosis, we investigated AKT. Both AKT and i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Suzuki, Seigo, Naito, Akihiro, Asano, Takayuki, Evans, Teresa T., Reddy, Shrikanth A. G., Higuchi, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562876/
https://ncbi.nlm.nih.gov/pubmed/18468786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.03.020
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker