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ML327 Induces Apoptosis and Sensitizes Ewing Sarcoma Cells to TNF-Related Apoptosis-Inducing Ligand

Ewing sarcomas are rare mesenchymal-derived bone and soft tissue tumors in children. Afflicted children with distant metastases have poor survival despite aggressive therapeutics. Epithelial-to-mesenchymal transition in epithelial carcinomas is associated with loss of E-cadherin and resistance to ap...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Rellinger, Eric J., Padmanabhan, Chandrasekhar, Qiao, Jingbo, Appert, Andrew, Waterson, Alex G., Lindsley, Craig W., Beauchamp, R. Daniel, Chung, Dai H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564678/
https://ncbi.nlm.nih.gov/pubmed/28716733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.07.050
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