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Constitutively active Rheb induces oncogenic transformation

Rheb (Ras homolog enriched in brain) is a component of the phosphatidylinositol 3-kinase (PI3K)–target of rapamycin (TOR) signaling pathway, functioning as a positive regulator of TOR. Constitutively active mutants of Rheb induce oncogenic transformation in cell culture. The transformed cells are la...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jiang, Hao, Vogt, Peter K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562864/
https://ncbi.nlm.nih.gov/pubmed/18521078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.180
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