Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine

The chemical reactivity, toxicology and pharmacological responses to nitroxyl (HNO) are often distinctly different from those of nitric oxide (NO). The discovery that HNO donors may have pharmacological utility for treatment of cardiovascular disorders such as heart failure and ischemia reperfusion...

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Detalhes bibliográficos
Main Authors: Donzelli, Sonia, Espey, Michael G., Flores-Santana, Wilmarie, Switzer, Christopher H., Yeh, Grace C., Huang, S. Jinming, Stuehr, Dennis J., King, S. Bruce, Miranda, Katrina M., Wink, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562766/
https://ncbi.nlm.nih.gov/pubmed/18503778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.04.036
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