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Insertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomas

In this study we have exploited the power of insertional mutagenesis to elucidate tumor progression pathways in mice carrying two oncogenes (MYC/Runx2) that collaborate to drive early lymphoma development. Neonatal infection of these mice with Moloney murine leukemia virus (MLV) resulted in accelera...

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Detalhes bibliográficos
Main Authors: Stewart, Monica, Mackay, Nancy, Hanlon, Linda, Blyth, Karen, Scobie, Linda, Cameron, Ewan, Neil, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562448/
https://ncbi.nlm.nih.gov/pubmed/17545590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0433
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