Development of a small molecule serum and glucocorticoid-regulated kinase 1 antagonist and its evaluation as a prostate cancer therapeutic

Androgens, through their actions on the androgen receptor (AR), are required for the development of the prostate and contribute to the pathological growth dysregulation observed in prostate cancers. Consequently, androgen ablation has become an essential component of the pharmacotherapy of prostate...

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Detalhes bibliográficos
Main Authors: Sherk, Andrea B., Frigo, Daniel E., Schnackenberg, Christine G., Bray, Jeffrey D., Laping, Nicholas J., Trizna, Walter, Hammond, Marlys, Patterson, Jaclyn R., Thompson, Scott K., Kazmin, Dmitri, Norris, John D., McDonnell, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562281/
https://ncbi.nlm.nih.gov/pubmed/18794135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1047
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