Research Resource: Transcriptional Profiling in a Cellular Model of Breast Cancer Reveals Functional and Mechanistic Differences Between Clinically Relevant SERM and Between SERM/Estrogen Complexes

Exploitation of the relationship between estrogen receptor (ER) structure and activity has led to the development of 1) selective ER modulators (SERM), compounds whose relative agonist/antagonist activities differ between target tissues; 2) selective ER degraders (SERD), compounds that induce a conf...

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Autori principali: Wardell, Suzanne E., Kazmin, Dmitri, McDonnell, Donald P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2012
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Research Resource
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385791/
https://ncbi.nlm.nih.gov/pubmed/22570330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1031
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