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Effect of CpG Oligonucleotides on Vaccine-induced B Cell Memory

Adding synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs to Anthrax Vaccine Adsorbed (AVA, the licensed human vaccine) increases the speed and magnitude of the resultant Ab response. Ab titers persist in the protective range for >1 year, significantly longer than in animals...

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Détails bibliographiques
Auteurs principaux: Tross, Debra, Klinman, Dennis M.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562272/
https://ncbi.nlm.nih.gov/pubmed/18832738
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