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Acid Sphingomyelinase Promotes Lipoprotein Retention within Early Atheromata and Accelerates Lesion Progression
OBJECTIVE: The key initial step in atherogenesis is the subendothelial retention of apolipoprotein B-containing lipoproteins. Acid sphingomyelinase (acid SMase), an enzyme present extracellularly within the arterial wall, strongly enhances lipoprotein retention in model systems in vitro, and retaine...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562252/ https://ncbi.nlm.nih.gov/pubmed/18669882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.173344 |
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