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Acid Sphingomyelinase Promotes Lipoprotein Retention within Early Atheromata and Accelerates Lesion Progression

OBJECTIVE: The key initial step in atherogenesis is the subendothelial retention of apolipoprotein B-containing lipoproteins. Acid sphingomyelinase (acid SMase), an enzyme present extracellularly within the arterial wall, strongly enhances lipoprotein retention in model systems in vitro, and retaine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Devlin, Cecilia M., Leventhal, Andrew R., Kuriakose, George, Schuchman, Edward H., Williams, Kevin Jon, Tabas, Ira
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562252/
https://ncbi.nlm.nih.gov/pubmed/18669882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.173344
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