Novel Microtubule-Interacting Phenoxy Pyridine and Phenyl Sulfanyl Pyridine Analogues for Cancer Therapy

Current microtubule inhibitory agents used in the clinic to treat cancer have severe side effects, and development of resistance is frequent. We have evaluated the antitumor effect of a novel 30-compound library of phenoxy pyridine and phenyl sulfanyl pyridine derivatives. MTT assays revealed that,...

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Hauptverfasser: Anchoori, Ravi Kumar, Kortenhorst, Madeleine Susanne Quirine, Hidalgo, Manuel, Sarkar, Taradas, Hallur, Gurulingappa, Bai, Ruoli, Van Diest, Paul J., Hamel, Ernest, Khan, Saeed R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562226/
https://ncbi.nlm.nih.gov/pubmed/18778046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800203e
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