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Enantioselective Synthesis of (+)-Chamaecypanone C, a Novel Microtubule Inhibitor
A number of bicyclo[2.2.2]octenone-containing natural products have been isolated from the heartwood of Chamaecyparis obtusa var. formosana (Figure 1) including the Diels-Alder adducts[1] obtunone (1),[2] chamaecypanone C (2),[3] and the [4+2] dimer (+)-3.[2],[4] Compound (+)-2 was shown to exhibit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747729/ https://ncbi.nlm.nih.gov/pubmed/19140149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200805486 |
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