Polyoma virus mutant with normal transforming ability but impaired tumorigenic potential.

Cloned DNA from the P155 mutant of polyoma virus transforms cells in culture as efficiently as wild-type DNA, but has a much lower tumorigenic potential when injected into newborn rats. Like cells transformed by wild-type DNA, cells transformed by the mutant DNA grow in low serum concentrations, for...

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Bibliografske podrobnosti

izdano v:	J Virol
Principais autores:	Gelinas, C, Chartrand, P, Bastin, M
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1982
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6292450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.43.3.1072-1081.1982
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