Polyoma virus mutant with normal transforming ability but impaired tumorigenic potential.
Cloned DNA from the P155 mutant of polyoma virus transforms cells in culture as efficiently as wild-type DNA, but has a much lower tumorigenic potential when injected into newborn rats. Like cells transformed by wild-type DNA, cells transformed by the mutant DNA grow in low serum concentrations, for...
Spremljeno u:
| Izdano u: | J Virol |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1982
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6292450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.43.3.1072-1081.1982 |
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