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Polyoma virus mutant with normal transforming ability but impaired tumorigenic potential.

Cloned DNA from the P155 mutant of polyoma virus transforms cells in culture as efficiently as wild-type DNA, but has a much lower tumorigenic potential when injected into newborn rats. Like cells transformed by wild-type DNA, cells transformed by the mutant DNA grow in low serum concentrations, for...

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Bibliografiset tiedot
Päätekijät: Gelinas, C, Chartrand, P, Bastin, M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1982
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC256219/
https://ncbi.nlm.nih.gov/pubmed/6292450
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