Disruption of the Plasmodium falciparum PfPMT Gene Results in a Complete Loss of Phosphatidylcholine Biosynthesis via the Serine-Decarboxylase-Phosphoethanolamine-Methyltransferase Pathway and Severe Growth and Survival Defects

Biochemical studies in the human malaria parasite, Plasmodium falciparum, indicated that in addition to the pathway for synthesis of phosphatidylcholine from choline (CDP-choline pathway), the parasite synthesizes this major membrane phospholipid via an alternative pathway named the serine-decarboxy...

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Bibliografiset tiedot
Päätekijät: Witola, William Harold, El Bissati, Kamal, Pessi, Gabriella, Xie, Changan, Roepe, Paul D., Mamoun, Choukri Ben
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2008
Aiheet:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562060/
https://ncbi.nlm.nih.gov/pubmed/18694927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804360200
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