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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated Impairment of B cell Differentiation Involves Dysregulation of Paired Box 5 (Pax5) Isoform, Pax5a
The persistent environmental contaminant and immunotoxicant, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), markedly suppresses humoral immune responses. We recently reported impaired down-regulation of paired box 5 (Pax5), a repressor of B cell differentiation and concomitant suppression of the immuno...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562000/ https://ncbi.nlm.nih.gov/pubmed/18483191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.139857 |
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