2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated Impairment of B cell Differentiation Involves Dysregulation of Paired Box 5 (Pax5) Isoform, Pax5a

The persistent environmental contaminant and immunotoxicant, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), markedly suppresses humoral immune responses. We recently reported impaired down-regulation of paired box 5 (Pax5), a repressor of B cell differentiation and concomitant suppression of the immuno...

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Hlavní autoři: Schneider, Dina, Manzan, Maria A., Crawford, Robert B., Chen, Weimin, Kaminski, Norbert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562000/
https://ncbi.nlm.nih.gov/pubmed/18483191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.139857
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