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Formation of Two Novel Estrogen Guanine Adducts and HPLC/MS Detection of 4-Hydroxyestradiol-N(7)-Guanine in Human Urine
Estrogen-DNA adducts are potential biomarkers for assessing the risk of developing of a number of hormonally-modified cancers, including breast cancer. Formation of the 4-hydroxyestradiol-N(7)-guanine (4-OHE(2)-N(7)-guanine) adduct from reaction of estradiol-3,4-quinone with DNA and its detection in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561950/ https://ncbi.nlm.nih.gov/pubmed/18582124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800145w |
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