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Quantification of Sulforaphane Mercapturic Acid Pathway Conjugates in Human Urine by High-Performance Liquid Chromatography and Isotope-Dilution Tandem Mass Spectrometry

We report validation of the first high-pressure liquid chromatography isotope-dilution mass spectrometry method to measure sulforaphane (SFN) and its glutathione-derived conjugates in human urine. As epidemiological evidence continues to mount that the consumption of a diet rich in cruciferous veget...

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Autori principali: Egner, Patricia A., Kensler, Thomas W., Chen, Jian-Guo, Gange, Stephen J., Groopman, John D., Friesen, Marlin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082854/
https://ncbi.nlm.nih.gov/pubmed/18729326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800210k
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