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Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

Nephrons, the basic functional units of the kidney, are generated repetitively during kidney organogenesis from a mesenchymal progenitor population. Which cells within this pool give rise to nephrons and how multiple nephron lineages form during this protracted developmental process is unclear. We d...

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Autori principali: Kobayashi, Akio, Valerius, M. Todd, Mugford, Joshua W., Carroll, Thomas J., Self, Michelle, Oliver, Guillermo, McMahon, Andrew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561900/
https://ncbi.nlm.nih.gov/pubmed/18682239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.05.020
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