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Macrophages pulsed with Streptococcus pneumoniae elicit a T cell-dependent antibody response upon transfer into naïve mice
Macrophages are less effective than DC at priming naïve CD4+ T cells, suggesting that DC are unique in initiating T cell-dependent antibody responses. We compared the ability of DC and macrophages, pulsed in vitro with Streptococcus pneumoniae (Pn), to elicit protein- and polysaccharide (PPS)-specif...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561269/ https://ncbi.nlm.nih.gov/pubmed/18641316 |
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