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Macrophages pulsed with Streptococcus pneumoniae elicit a T cell-dependent antibody response upon transfer into naïve mice

Macrophages are less effective than DC at priming naïve CD4+ T cells, suggesting that DC are unique in initiating T cell-dependent antibody responses. We compared the ability of DC and macrophages, pulsed in vitro with Streptococcus pneumoniae (Pn), to elicit protein- and polysaccharide (PPS)-specif...

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Main Authors: Vasilevsky, Sam, Colino, Jesus, Puliaev, Roman, Canaday, David H., Snapper, Clifford M.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561269/
https://ncbi.nlm.nih.gov/pubmed/18641316
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