Decreased 4-1BB expression on CD4+CD25(high) regulatory T cells in peripheral blood of patients with multiple sclerosis

As a tumour necrosis factor receptor superfamily member, 4-1BB (CD137) is preferentially expressed in CD4+CD25+ regulatory T cells (Tregs) and has been suggested to play an important role in regulating the generation or function of Tregs. Recent studies of human Tregs have shown that blood CD4+CD25(...

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Detalhes bibliográficos
Main Authors: Liu, G-Z, Gomes, A C, Fang, L-B, Gao, X-G, Hjelmstrom, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Translational Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561085/
https://ncbi.nlm.nih.gov/pubmed/18727631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03730.x
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