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Decreased 4-1BB expression on CD4+CD25(high) regulatory T cells in peripheral blood of patients with multiple sclerosis

As a tumour necrosis factor receptor superfamily member, 4-1BB (CD137) is preferentially expressed in CD4+CD25+ regulatory T cells (Tregs) and has been suggested to play an important role in regulating the generation or function of Tregs. Recent studies of human Tregs have shown that blood CD4+CD25(...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, G-Z, Gomes, A C, Fang, L-B, Gao, X-G, Hjelmstrom, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561085/
https://ncbi.nlm.nih.gov/pubmed/18727631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03730.x
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