The N-terminal domain of MyoD is necessary and sufficient for its nuclear localization-dependent degradation by the ubiquitin system

A growing number of proteins, including the myogenic transcription factor MyoD, are targeted for proteasomal degradation after N-terminal ubiquitination (NTU) where the first ubiquitin moiety is conjugated to the N-terminal residue rather than to an internal lysine. NTU might be essential in targeti...

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Bibliographic Details
Main Authors: Sadeh, Ronen, Breitschopf, Kristin, Bercovich, Beatrice, Zoabi, Muhammad, Kravtsova-Ivantsiv, Yelena, Kornitzer, Daniel, Schwartz, Alan, Ciechanover, Aaron
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2560994/
https://ncbi.nlm.nih.gov/pubmed/18836078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808373105
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