ICOS Costimulation Expands Th2 Immunity by Augmenting Migration of Lymphocytes to Draining Lymph Nodes

The T cell costimulatory molecule ICOS regulates Th2 effector function in allergic airway disease. Recently, several studies with ICOS(−/−) mice have also demonstrated a role for ICOS in Th2 differentiation. To determine the effects of ICOS on the early immune response, we investigated augmenting IC...

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Main Authors: Tesciuba, Amanda G., Shilling, Rebecca A., Agarwal, Monica D., Bandukwala, Hozefa S., Clay, Bryan S., Moore, Tamson V., Weinstock, Joel V., Welcher, Andrew A., Sperling, Anne I.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2560985/
https://ncbi.nlm.nih.gov/pubmed/18606653
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