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Inducible Costimulator Controls Migration of T Cells to the Lungs via Down-Regulation of CCR7 and CD62L
We and others reported that Inducible costimulator-deficient (ICOS(−/−)) mice manifest a defect in Th2-mediated airway inflammation, which was attributed to reduced Th2 differentiation in the absence of ICOS signaling. Interestingly, the number of CD4 T cells present in the airways and lungs after s...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Thoracic Society
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208611/ https://ncbi.nlm.nih.gov/pubmed/21421907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0466OC |
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