Isolation and preliminary characterization of a phosphonoacetic acid-resistant and temperature-sensitive mutant of herpes simplex virus type 1.

A group of 43 phosphonoacetic acid (PAA)-resistant mutants of herpes simplex virus type 1 was isolated after the mutagenesis of infected cells with nitrosoguanidine. One of these mutants, designated PAA1rts1, was found to be temperature sensitive (ts), that is, unable to replicate at 39.5 degrees C,...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Daksis, J I, Priemer, M M, Chan, V L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6283139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.42.1.20-29.1982
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