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Isolation and preliminary characterization of a phosphonoacetic acid-resistant and temperature-sensitive mutant of herpes simplex virus type 1.

A group of 43 phosphonoacetic acid (PAA)-resistant mutants of herpes simplex virus type 1 was isolated after the mutagenesis of infected cells with nitrosoguanidine. One of these mutants, designated PAA1rts1, was found to be temperature sensitive (ts), that is, unable to replicate at 39.5 degrees C,...

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Bibliographic Details
Published in:J Virol
Main Authors: Daksis, J I, Priemer, M M, Chan, V L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256040/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6283139/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.42.1.20-29.1982
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