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Knockdown of MBP-1 in Human Foreskin Fibroblasts Induces p53-p21 Dependent Senescence
MBP-1 acts as a general transcriptional repressor. Overexpression of MBP-1 induces cell death in a number of cancer cells and regresses tumor growth. However, the function of endogenous MBP-1 in normal cell growth regulation remains unknown. To unravel the role of endogenous MBP-1, we knocked down M...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2557062/ https://ncbi.nlm.nih.gov/pubmed/18852884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003384 |
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