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Hepatitis C Virus NS5A Physically Associates with p53 and Regulates p21/waf1 Gene Expression in a p53-Dependent Manner

We have previously demonstrated that hepatitis C virus (HCV) NS5A protein promotes cell growth and transcriptionally regulates the p21/waf1 promoter, a downstream effector gene of p53. In this study, we investigated the molecular mechanism of NS5A-mediated transcriptional repression of p21/waf1. We...

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Autors principals: Majumder, Mainak, Ghosh, Asish K., Steele, Robert, Ray, Ranjit, Ray, Ratna B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114046/
https://ncbi.nlm.nih.gov/pubmed/11152513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1401-1407.2001
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