p53 activation by knockdown technologies.
Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms to study gene function by sequence-specific knockdown. Both technologies, however, can elicit undesirable off-target effects. We have used several model genes to study these...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2007-05-01
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| Serier: | PLoS Genetics |
| Online adgang: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.0030078&type=printable |
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