p53 activation by knockdown technologies.

Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms to study gene function by sequence-specific knockdown. Both technologies, however, can elicit undesirable off-target effects. We have used several model genes to study these...

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書誌詳細

主要な著者:	Mara E Robu, Jon D Larson, Aidas Nasevicius, Soraya Beiraghi, Charles Brenner, Steven A Farber, Stephen C Ekker
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2007-05-01
シリーズ:	PLoS Genetics
オンライン･アクセス:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.0030078&type=printable
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